Drug Hunter Categories and List of Cheat Sheets
List of Content Categories | List of Cheat Sheets
Drug Hunter original content generally falls into a few categories, summarized below. A list of cheat sheets is also summarized below and on the resources page for ease of navigation.
List of Content Categories
| Name | Notes | |
|---|---|---|
| Cheat Sheets | https://drughunter.com/category/cheatsheets/# | Contain page-sized graphics with information (e.g. Approved Covalent Drugs, LogD Cheat Sheet, Topliss Scheme, PK Cheat Sheet) |
| Case Studies | https://drughunter.com/category/case-studies/# | Discussions of specific drug discovery programs or drug syntheses (e.g. Voxelotor, Pembrolizumab, Imatinib) |
| Articles | https://drughunter.com/category/articles/# | Discussions of specific topics related to drug discovery topics (e.g. Chimeric Degraders, Lead-Finding) |
| Companies | https://drughunter.com/category/drugdiscoverycompanies/# | Highlights or summaries of drug discovery companies (e.g. 2019 Small Molecule and Biologic Biotech IPOs) |
| Highlights | https://drughunter.com/category/highlights/# | Highlights of scientific advances in the industry (e.g. Small Molecules of the Month, 2019 Biologic Drug Approvals) |
| Fundamentals | https://drughunter.com/category/fundamentals/# | Discussions of fundamental concepts related to drug discovery (e.g. Square-Cube Law, Why LogD Matters, Topliss Cheat Sheets, What is a Biologic Drug?) |
| Perspectives | https://drughunter.com/category/perspectives/# | Discussions of drug discovery industry practices (e.g. Don’t Work on Things That Don’t Work) |
| Chemistry | https://drughunter.com/category/chemistry/# | Topics tailored to a chemistry audience (e.g. Pd-Couplings Cheat Sheet, Adventures in Atropisomerism) |
List of Cheat Sheets
| Name | Notes | |
|---|---|---|
| LogD Cheat Sheet | https://drughunter.com/logdsheet/# | Summary of expected LogD and potency shifts expected from common functional group additions |
| PK Cheat Sheet | https://drughunter.com/pk-cheat-sheet/# | Summary of important parameters when considering in vivo studies |
| Topliss Scheme | https://drughunter.com/topliss/# | Graphical summary of the Topliss design scheme |
| Approved Covalent Drug Mechanisms | https://drughunter.com/covalents1/# | Summary of mechanisms of approved covalent drugs |
| Pd-Couplings Cheat Sheet | https://drughunter.com/pd-couplings-cheat-sheet/# | Summary of common Pd-coupling conditions to try first |
| Unusual Molecular Interactions | https://drughunter.com/pdbgems/# | Summary of unusual molecular interactions detected in X-ray co-crystal structures of inhibitors |
| Bioactivation of Structural Alerts | https://drughunter.com/bioactivation-of-structural-alerts/# | Summary of mechanisms of bioactivation of common structural alerts |
| Managing DILI Risk | https://drughunter.com/dilirisk/# | Summary of assays and strategies used to mitigate idiosyncratic liver toxicity |
| Kinase Inhibitor Classes | https://drughunter.com/kinase-inhibitor-types-predicted-with-machine-learning/# | Summary of binding modes of Type I-II kinase inhibitors |
| 2019 Small Molecule Approvals | https://drughunter.com/2019newdrugs/# | Summary of 2019 approved small molecule drugs |
| 2019 Biologic Drug Approvals | https://drughunter.com/2019biologics/# | Summary of 2019 approved biologics |
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